Innovative and Informative Provision for the Economic Security of Enterprises under COVID-19 challenges

The COVID-19 pandemic, in the current conditions of globalization challenges, turned out to be one of the general reasons for a significant decrease in the level of economic security of economic systems, including at the level of companies. This updates the issue of guaranteeing the economic security of companies. The study aims to develop the conceptual and methodological foundations of the innovative and investment provision of the economic security of companies in the conditions of the challenges of COVID-19. The methodological principles of innovative and informative provision of the economic security of companies are based on a systemic approach, which allows considering the company as an open system in which economic security is one of the determining subsystems. It has been shown that the economic security of the company must ensure the achievement of the socio-economic goals set for the company in the conditions of the challenges of the COVID-19 pandemic, protecting the company from adverse factors and the negative impact of internal and external changes. It is emphasized that innovation is a determining factor of the economic development of the company, and therefore of economic security. The staggering of systematic steps to make management decisions is suggested to ensure the economic security of the company in the conditions of the challenges of COVID-19.

[Clinical and anatomical analysis of mortality from COVID-19 in sudden death and in those who died in health care facilities]. / Kliniko-anatomicheskii analiz letal'nosti ot COVID-19 pri skoropostizhnoi smerti i u umershikh v lechebno-profilakticheskikh uchrezhdeniyakh.

OBJECTIVE: Assessment of pathological and morphological changes in those who died from COVID-19 including persons received therapy in medical and preventive institutions (LPI) and who died suddenly from this pathology at home. The analysis data of the pathological and anatomical changes in 57 deaths from COVID-19 in hospitals and 74 forensic medical examinations where infectious pathology was established as the main cause of death are presented. For microscopy the sections were stained with hemotoxylin and eosin, OCG, immunohistochemical study with markers for CD3, CD 4, CD 20, SK-7. The mixed viral and bacterial lesions of the lungs were detected more often than pure viral infection in those who died suddenly from COVID-19 compared with people whose death occurred in medical facilities. This allows speaking about the lack of adequate antibiotic therapy out-patiently. Features of mononuclear lung infiltration in COVID-19 with a predominance of a moderately pronounced reaction of T-lymphocytes and a mild B-lymphocytic reaction indicate a decrease in immunological reactivity. Conducting clinical and anatomical analysis allows determining the features of pathogenesis and morphogenesis in each specific fatal case and informing the clinicians of health facilities (clinics and hospitals) allows the autopsy doctor (pathologist, forensic physician) to provide significant assistance in improving the quality of diagnosis and treatment of patients with this highly contagious severe viral disease.